品牌 |
Leading Biology |
貨號 |
LM20613 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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形式 |
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
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濃度 |
Purified truncated recombinant LPP-His is expressed in E. coli strain BL21 (DE3). |
純度 |
Mouse |
復(fù)溶 |
Petit M.M.R.,et al.Genomics 36:118-129(1996).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lemke I.,et al.Cytogenet. Cell Genet. 95:153-156(2001).
Petit M.M.,et al.Cancer Genet. Cytogenet. 106:18-23(1998).
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儲存條件 |
Human
|
儲存溶液 |
Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP
|
應(yīng)用 |
ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000) ,
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產(chǎn)品描述 |
Function
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
Cellular_Location
Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1
Tissue_Location
Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes
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數(shù)量 |
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