品牌 |
Leading Biology | 貨號 |
LM20607 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
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濃度 |
LDB3 (AAH10929, 1 a.a. ~ 283 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
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純度 |
Mouse |
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試劑準備 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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復(fù)溶 |
A novel custom resequencing array for dilated cardiomyopathy. Zimmerman RS, et al. Genet Med, 2010 May. PMID 20474083.Common susceptibility variants examined for association with dilated cardiomyopathy. Rampersaud E, et al. Ann Hum Genet, 2010 Mar. PMID 20201937.Differences in aberrant expression and splicing of sarcomeric proteins in the myotonic dystrophies DM1 and DM2. Vihola A, et al. Acta Neuropathol, 2010 Apr. PMID 20066428.Candidate-gene testing for orphan limb-girdle muscular dystrophies. Aurino S, et al. Acta Myol, 2008 Dec. PMID 19472918.Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. Arimura T, et al. Cardiovasc Res, 2009 Jul 1. PMID 19377068.
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儲存條件 |
Human
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儲存溶液 |
LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)
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應(yīng)用 |
WB~~1:500~1000
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數(shù)量 |
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選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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¥5096.00 | 訂購 詢價 | |
2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
¥4950.00 | 訂購 詢價 | |
3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
¥3243.00 | 訂購 詢價 | |||
4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
¥3243.00 | 訂購 詢價 | |
5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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¥4015.00 | 訂購 詢價 | |
6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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¥5096.00 | 訂購 詢價 |
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