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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > KRTHB1 Antibody (monoclonal) (M01)

KRTHB1 Antibody (monoclonal) (M01)

LM20589
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

KRTHB1 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號(hào)

LM20589

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

濃度

KRTHB1 (AAH21241, 1 a.a. ~ 202 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA. Gilon M, et al. Differentiation, 2008 May. PMID 18021261.New consensus nomenclature for mammalian keratins. Schweizer J, et al. J Cell Biol, 2006 Jul 17. PMID 16831889.Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.Keratins of the human hair follicle. Langbein L, et al. Int Rev Cytol, 2005. PMID 15797458.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Keratin, type II cuticular Hb1, Hair keratin K29, Keratin, hair, basic, Keratin-81, K81, Metastatic lymph node 137 gene protein, MLN 137, Type II hair keratin Hb1, Type-II keratin Kb21, ghHKb1, ghHb1, KRT81, KRTHB1, MLN137

應(yīng)用

WB~~1:500~1000

數(shù)量

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