品牌 |
Leading Biology |
貨號(hào) |
LM20562 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
|
形式 |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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濃度 |
Human KRT18 |
純度 |
Mouse |
復(fù)溶 |
Oshima R.G.,et al.Differentiation 33:61-68(1986).
Kim J.W.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Kulesh D.A.,et al.Mol. Cell. Biol. 8:1540-1550(1988).
|
儲(chǔ)存條件 |
Human
|
儲(chǔ)存溶液 |
Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
|
應(yīng)用 |
ELISA (1:10000), IHC-P (1:200-1:400), WB (1:500-1:2000)
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產(chǎn)品描述 |
Function
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Cellular_Location
Cytoplasm, perinuclear region. Nucleus, nucleolus
Tissue_Location
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
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數(shù)量 |
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