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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20520 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
This gene encodes a major cytoplasmic protein which is theonly known constituent common to submembranous plaques of bothdesmosomes and intermediate junctions. This protein forms distinctcomplexes with cadherins and desmosomal cadherins and is a memberof the catenin family since it contains a distinct repeating aminoacid motif called the armadillo repeat. Mutation in this gene hasbeen associated with Naxos disease. Alternative splicing occurs inthis gene; however, not all transcripts have been fully described.
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濃度 |
This JUP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 636-663 amino acids from human JUP . |
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純度 |
Mouse |
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試劑準(zhǔn)備 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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復(fù)溶 |
Fressart, V., et al. Europace 12(6):861-868(2010)
Cabral, R.M., et al. J. Invest. Dermatol. 130(6):1543-1550(2010)
Aktary, Z., et al. Oncogene 29(14):2118-2129(2010)
Pryczynicz, A., et al. Folia Histochem. Cytobiol. 48(1):128-133(2010)
Czyzewska, J., et al. Folia Histochem. Cytobiol. 48(1):37-45(2010)
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
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應(yīng)用 |
WB~~1:100~1600
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產(chǎn)品描述 |
Function
Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
Cellular_Location
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Cytoplasmic in a soluble and membrane-associated form
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數(shù)量 |
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| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購(gòu) 詢價(jià) | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 訂購(gòu) 詢價(jià) | |
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