品牌 |
Leading Biology |
貨號 |
LM20491 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
Inositol polyphosphate 4-phosphatase (INPP4A), an enzyme of the inositol phosphate signaling pathway, catalyzes the hydrolysis of the 4-position phosphate of inositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and phosphatidylinositol 3,4-bisphosphate (1). Hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate has been implicated in mitogenesis mediated by PDGF receptor, the oxidative burst of neutrophils, and translocation of the glucose transporter to the plasma membrane (2).
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濃度 |
A synthetic peptide corresponding to residues near the C-terminus of human INPP4A was used as an immunogen. |
純度 |
Rabbit |
試劑準(zhǔn)備 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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復(fù)溶 |
1. The UniProt Consortium, The Universal Protein Resource (UniProt), Nucleic Acids Res. 36:D190-D195 (2008)<br>2. Norris et al. J Biol Chem 270(27):16128-33, 1995<br>
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儲存條件 |
Human, Mouse, Rat
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儲存溶液 |
Type I inositol 3, 4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type I, INPP4A
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應(yīng)用 |
WB~~1:1000~2000
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產(chǎn)品描述 |
Function
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.
Tissue_Location
Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain.
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數(shù)量 |
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