品牌 |
Leading Biology |
貨號 |
LM20472 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
形式 |
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
|
濃度 |
This IHH Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IHH. |
純度 |
Mouse |
試劑準(zhǔn)備 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
|
復(fù)溶 |
van Dop, W.A., et al. Gastroenterology 139(5):1665-1676(2010) Koike, S., et al. Biochem. Biophys. Res. Commun. 400(1):66-71(2010) Rice, D.P., et al. Hum. Mol. Genet. 19(17):3457-3467(2010) Witte, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14211-14216(2010) Lyashenko, N., et al. Dev. Dyn. 239(8):2266-2277(2010)
|
儲存條件 |
Human
|
儲存溶液 |
Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
|
應(yīng)用 |
WB~~1:500~8000
|
產(chǎn)品描述 |
Function
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
Cellular_Location
Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.
Tissue_Location
Expressed in embryonic lung, and in adult kidney and liver
|
數(shù)量 |
|