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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > IGFBP7 Antibody

IGFBP7 Antibody

LM20469
貨號 貨期 規(guī)格 / 價格 詢價

IGFBP7 Antibody

品牌

Leading Biology

貨號

LM20469

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ; ; ;

純度

Mouse

復(fù)溶

1. Sci Signal. 2012 Dec 18;5(255):ra92. 2. Cancer Biol Ther. 2012 Feb 1;13(3):148-55.

儲存條件

Human

儲存溶液

Insulin-like growth factor-binding protein 7, IBP-7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor, TAF, IGFBP7, MAC25, PSF

應(yīng)用

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

產(chǎn)品描述

Function Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Cellular_Location Secreted.

數(shù)量

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