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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > GNAI1 Antibody (monoclonal) (M01)

GNAI1 Antibody (monoclonal) (M01)

LM20404
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

GNAI1 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號(hào)

LM20404

產(chǎn)品分類

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).

濃度

GNAI1 (AAH26326, 1 a.a. ~ 354 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準(zhǔn)備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復(fù)溶

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.CK beta 8/CCL23 induces cell migration via the Gi/Go protein/PLC/PKC delta/NF-kappa B and is involved in inflammatory responses. Kim J, et al. Life Sci, 2010 Feb 27. PMID 19951712.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Altered G-protein coupling in an mGluR6 point mutant associated with congenital stationary night blindness. Beqollari D, et al. Mol Pharmacol, 2009 Nov. PMID 19666700.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Guanine nucleotide-binding protein G(i) subunit alpha-1, Adenylate cyclase-inhibiting G alpha protein, GNAI1

應(yīng)用

WB~~1:500~1000

數(shù)量

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