品牌 |
Leading Biology |
貨號 |
LM20398 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
Golgi Matrix Protein (GM130) is peripheral cytoplasmic protein that is bound to the Golgi membranes. It has been implicated as a maintainer of cis-Golgi structure (1). During mitosis, it regulates the disassembly and reassembly of the Golgi complex. It is also linked to docking and fusion of coatomer (COP I) coated vesicles to the Golgi membrane (2). The COOH-terminal domain of GM130 is highly homologous to Golgi human auto-antigen, golgin-95. GM130 interacts specifically and GTP-dependent manner with Rab1b protein, a regulator of anterograde traffic between ER and Golgi membranes (3). GM130 is also activator of YSK1, an essential player in cell migration.
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濃度 |
A synthetic peptide corresponding to residues in human Golgi Matrix Protein (GM130) was used as a immunogen. |
純度 |
Rabbit |
試劑準備 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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復(fù)溶 |
1. Nakamura N, et al. J Cell Biol 131:1715-1726, 1995<br>2. Warren G, Annual Rev Biochem 62:323-348, 1993<br>3. Weide T, et al. EMBO Rep 2:336-341, 2001<br>
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儲存條件 |
Human
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儲存溶液 |
Golgin subfamily A member 2, 130 kDa cis-Golgi matrix protein, GM130, GM130 autoantigen, Golgin-95, GOLGA2
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應(yīng)用 |
WB~~1:500~1000
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產(chǎn)品描述 |
Function
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
Cellular_Location
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein
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數(shù)量 |
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