品牌 |
Leading Biology |
貨號 |
LM20394 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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形式 |
May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
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濃度 |
Human GIMAP4 |
純度 |
Mouse |
復(fù)溶 |
Cambot M.,et al.Blood 99:3293-3301(2002).
Liu Y.Q.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schwefel D.,et al.Structure 21:550-559(2013).
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儲存條件 |
Human
|
儲存溶液 |
GTPase IMAP family member 4, Immunity-associated nucleotide 1 protein, IAN-1, hIAN1, Immunity-associated protein 4, GIMAP4, IAN1, IMAP4
|
應(yīng)用 |
Flo (1:100), IF (1:100), IHC-P (10 μg/ml), WB (1:2000) ,
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產(chǎn)品描述 |
Function
May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
Cellular_Location
Cytoplasm, cytosol
Tissue_Location
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
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數(shù)量 |
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