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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
LM20372 |
產(chǎn)品分類(lèi) |
單克隆抗體 | 研究領(lǐng)域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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純度 |
Mouse |
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復(fù)溶 |
1.J Biol Chem. 2009 Sep 25;284(39):26716-24.2.Int J Oncol. 2007 Mar;30(3):751-5.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Frizzled-5, Fz-5, hFz5, FzE5, FZD5, C2orf31
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應(yīng)用 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
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產(chǎn)品描述 |
Function
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Interacts specifically with Wnt5A to induce the beta- catenin pathway.
Cellular_Location
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein Note=Localized at the plasma membrane and also found at the Golgi
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數(shù)量 |
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| 選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱(chēng) | 規(guī)格 | 分類(lèi) | 研究領(lǐng)域 | 說(shuō)明書(shū) | 數(shù)量 | 目錄價(jià) | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購(gòu) 詢(xún)價(jià) | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
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￥4950.00 | 訂購(gòu) 詢(xún)價(jià) | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
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￥3243.00 | 訂購(gòu) 詢(xún)價(jià) | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
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￥3243.00 | 訂購(gòu) 詢(xún)價(jià) | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
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￥4015.00 | 訂購(gòu) 詢(xún)價(jià) | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
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￥5096.00 | 訂購(gòu) 詢(xún)價(jià) |
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