品牌 |
Leading Biology |
貨號(hào) |
LM20368 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Store at -20°C.Stable for 12 months from date of receipt
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形式 |
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
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純度 |
Mouse |
試劑準(zhǔn)備 |
Ascites containing with 0.02% sodium azide and 50% glycerol.
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復(fù)溶 |
da Silva A.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:7493-7498(1997).
Musci M.A.,et al.J. Biol. Chem. 272:11674-11677(1997).
Krause M.,et al.J. Cell Biol. 149:181-194(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
ADAP;Adhesion and degranulation promoting adaptor protein;FYB 120/130;Fyb;FYB-120/130; FYB_HUMAN;FYN binding protein;FYN T binding protein;FYN-binding protein;FYN-T-binding protein;p120/p130;PRO0823;SLAP 130;SLAP-130;SLAP130;SLP 76 associated phosphoprotein; SLP-76-associated phosphoprotein;SLP76 associated phosphoprotein.
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應(yīng)用 |
WB~~1:500
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產(chǎn)品描述 |
Function
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Cellular_Location
Cytoplasm. Nucleus
Tissue_Location
Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues
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數(shù)量 |
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