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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > FGG Antibody

FGG Antibody

LM20346
貨號 貨期 規(guī)格 / 價格 詢價

FGG Antibody

品牌

Leading Biology

貨號

LM20346

產(chǎn)品分類

單克隆抗體

研究領域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

純度

Mouse

復溶

1. Biochemistry. 2009 Sep 15;48(36):8656-63. 2. Blood. 2009 Nov 5;114(19):3994-4001.

儲存條件

Human

儲存溶液

Fibrinogen gamma chain, FGG

應用

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400

產(chǎn)品描述

Function Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. Cellular_Location Secreted.

數(shù)量

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