全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
LM20335 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
|
||
形式 |
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
|
||
濃度 |
FBLIM1 (NP_060026, 270 a.a. ~ 373 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
||
純度 |
mouse |
||
試劑準(zhǔn)備 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
|
||
復(fù)溶 |
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling. Zhao J, et al. J Biol Chem, 2009 Dec 4. PMID 19833732.Migfilin, a molecular switch in regulation of integrin activation. Ithychanda SS, et al. J Biol Chem, 2009 Feb 13. PMID 19074766.Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. Lad Y, et al. J Biol Chem, 2008 Dec 12. PMID 18829455.Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome. Lai-Cheong JE, et al. J Invest Dermatol, 2008 Sep. PMID 18528435.Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma. Papachristou DJ, et al. Histopathology, 2007 Oct. PMID 17711449.
|
||
儲(chǔ)存條件 |
Human
|
||
儲(chǔ)存溶液 |
Filamin-binding LIM protein 1, FBLP-1, Migfilin, Mitogen-inducible 2-interacting protein, MIG2-interacting protein, FBLIM1, FBLP1
|
||
應(yīng)用 |
WB~~1:500~1000
|
||
數(shù)量 |
|
||
| 選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價(jià) | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
￥4950.00 | 訂購 詢價(jià) | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
￥3243.00 | 訂購 詢價(jià) | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
￥3243.00 | 訂購 詢價(jià) | |
| 5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
|
￥4015.00 | 訂購 詢價(jià) | |
| 6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
￥5096.00 | 訂購 詢價(jià) |
.jpg)
微信掃描二維碼，隨時(shí)隨地與小諾親密接觸，精彩活動(dòng)，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)