品牌 |
Leading Biology | 貨號(hào) |
LM20283 |
產(chǎn)品分類 |
單克隆抗體 | 研究領(lǐng)域 |
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形式 |
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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純度 |
Mouse |
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復(fù)溶 |
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31, C20orf49
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應(yīng)用 |
IHC-P (2.5 μg/ml)
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產(chǎn)品描述 |
Function
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Cellular_Location
Secreted. Endoplasmic reticulum lumen.
Tissue_Location
Expressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle.
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數(shù)量 |
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選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說(shuō)明書 | 數(shù)量 | 目錄價(jià) | |
1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
¥5096.00 | 訂購(gòu) 詢價(jià) | |
2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 單克隆抗體 | Chondrogenesis Markers |
|
¥4950.00 | 訂購(gòu) 詢價(jià) | |
3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 單克隆抗體 |
|
¥3243.00 | 訂購(gòu) 詢價(jià) | |||
4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 μl | 單克隆抗體 | Miscellaneous antibodies |
|
¥3243.00 | 訂購(gòu) 詢價(jià) | |
5 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 μl | 單克隆抗體 | Antibodies against components of the renin-angiotensin system |
|
¥4015.00 | 訂購(gòu) 詢價(jià) | |
6 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 μl | 單克隆抗體 | Antibodies against neurotransmitters |
|
¥5096.00 | 訂購(gòu) 詢價(jià) |
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