品牌 |
Leading Biology |
貨號 |
LM20277 |
產(chǎn)品分類 |
單克隆抗體 |
研究領域 |
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產(chǎn)品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. ; ;
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純度 |
Mouse |
復溶 |
1. J Dermatol Sci. 2012 Feb;65(2):102-9. 2. Am J Pathol. 2009 May;174(5):1629-37.
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儲存條件 |
Human
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儲存溶液 |
Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6, DSG3, CDHF6
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應用 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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產(chǎn)品描述 |
Function
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Cellular_Location
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
Tissue_Location
Epidermis, tongue, tonsil, esophagus and carcinomas
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數(shù)量 |
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