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DCTN4 Antibody

LM20252
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)

DCTN4 Antibody

品牌

Leading Biology

貨號(hào)

LM20252

產(chǎn)品分類(lèi)

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

純度

Mouse

復(fù)溶

1.Cell. 2008 Dec 26;135(7):1189-200. 2.J Biol Chem. 2006 May 19;281(20):14006-14.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

Dynactin subunit 4, Dyn4, Dynactin subunit p62, DCTN4

應(yīng)用

E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000

產(chǎn)品描述

Function Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Cellular_Location Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In skeletal muscles, demonstrates a punctate distribution along costameres (By similarity). Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.

數(shù)量

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