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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > Cytokeratin-10 Antibody

Cytokeratin-10 Antibody

LM20233
貨號 貨期 規(guī)格 / 價格 詢價

Cytokeratin-10 Antibody

品牌

Leading Biology

貨號

LM20233

產品分類

單克隆抗體

研究領域

產品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Cytokeratin 10 (CK10) is a heterotetramer of two type I and two type II keratins. CK10 is typically associated with cytokeratin 1 (CK1). CK10 is expressed in all suprabasal cell layers, and it is part of the acidic/high molecular weight keratin subfamily. Defects in CK10 cause Epidermolytic hyperkeratosis (EHK), a hereditary skin hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum (1). CK10 has also been linked to cause annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. CK10, along with CK14, 15, 16, and 20, can be used to determine if a neoplasm originated from an epithelial or non-epithelial origin, such as the determination of metastatic malignant tumors of epithelial origin (2).

濃度

A synthetic peptide corresponding to residues in the C-term of human Cytokeratin 10 was used as immunogen.

純度

Rabbit

試劑準備

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

復溶

1. McGowan, K, et al; Journal of Investigative Dermatology 126:1013<br>2. Lin, Y, et al; Modern Pathology 17:1129<br>

儲存條件

Human

儲存溶液

Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP

應用

WB~~1:500

產品描述

Tissue_Location Seen in all suprabasal cell layers including stratum corneum

數(shù)量

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