品牌 |
Leading Biology |
貨號(hào) |
LM20161 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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產(chǎn)品概述 |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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形式 |
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
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濃度 |
CDC42EP2 (NP_006770, 102 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
純度 |
mouse |
試劑準(zhǔn)備 |
Clear, colorless solution in phosphate buffered saline, pH 7.2.
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復(fù)溶 |
1.Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with CDC42 effector proteins.Schnack C, Danzer KM, Hengerer B, Gillardon F.Neuroscience. 2008 Jul 17;154(4):1450-7. Epub 2008 Feb 29.
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儲(chǔ)存條件 |
Human
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儲(chǔ)存溶液 |
Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
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應(yīng)用 |
WB~~1:500~1000
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數(shù)量 |
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