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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > CD2 Antibody [Clone BH1]

CD2 Antibody [Clone BH1]

LM20141
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)

CD2 Antibody [Clone BH1]

品牌

Leading Biology

貨號(hào)

LM20141

產(chǎn)品分類(lèi)

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at 2 to 8°C.Antibody is stable for 24 months.

形式

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

濃度

Human CD2 protein

純度

Mouse

試劑準(zhǔn)備

0.5 ml at 200ug/ml; Conjugated to AF488

復(fù)溶

1. Wang MY et. al. An effective immuno-magnetic method for bone marrow purging in T cell malignancies. Bone Marrow Transplant. 1992;9(5):319-23.

儲(chǔ)存條件

Human

儲(chǔ)存溶液

T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5, CD2, CD2, SRBC

產(chǎn)品描述

Function CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. Cellular_Location Membrane; Single-pass type I membrane protein

數(shù)量

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