品牌 |
Leading Biology |
貨號 |
LM20098 |
產(chǎn)品分類 |
單克隆抗體 |
研究領(lǐng)域 |
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形式 |
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
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濃度 |
Synthetic peptide corresponding to aa (EEEDVPGQAKDELC)of human Calreticulin |
純度 |
Mouse |
復(fù)溶 |
McCauliffe D.P.,et al.J. Clin. Invest. 85:1379-1391(1990).
Rokeach L.A.,et al.J. Immunol. 147:3031-3039(1991).
McCauliffe D.P.,et al.J. Biol. Chem. 267:2557-2562(1992).
Liu J.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
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儲存條件 |
Human, Monkey
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儲存溶液 |
Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60, CALR, CRTC
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應(yīng)用 |
ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000) ,
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產(chǎn)品描述 |
Function
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
Cellular_Location
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Note=Also found in cell surface (T cells), cytosol and extracellular matrix Associated with the lytic granules in the cytolytic T-lymphocytes
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數(shù)量 |
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