形式 |
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).
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復(fù)溶 |
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study. Tang W, et al. Blood, 2010 Aug 27. PMID 20802025.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation. Olivari S, et al. J Biol Chem, 2005 Jan 28. PMID 15579471.Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins. Mast SW, et al. Glycobiology, 2005 Apr. PMID 15537790.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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