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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > BGN Antibody (monoclonal) (M01)

BGN Antibody (monoclonal) (M01)

LM20072
貨號 貨期 規(guī)格 / 價格 詢價

BGN Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號

LM20072

產(chǎn)品分類

單克隆抗體

研究領域

產(chǎn)品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

濃度

BGN (AAH02416.1, 1 a.a. ~ 368 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

純度

mouse

試劑準備

Clear, colorless solution in phosphate buffered saline, pH 7.2.

復溶

Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation. Yang SN, et al. Arch Physiol Biochem, 2009 Jul. PMID 19580379.Biglycan expression in hypertensive subjects with normal or increased carotid intima-media wall thickness. Sardo MA, et al. Clin Chim Acta, 2009 Aug. PMID 19523462.ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan. Hiukka A, et al. Diabetes, 2009 Sep. PMID 19502413.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance. Kilts T, et al. Scand J Med Sci Sports, 2009 Aug. PMID 19422643.

儲存條件

Human

儲存溶液

Biglycan, Bone/cartilage proteoglycan I, PG-S1, BGN, SLRR1A

應用

WB~~1:500~1000

數(shù)量

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