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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > 單克隆抗體 > Anti-Mouse CD104 Antibody, clone 346-11A (RPE)

Anti-Mouse CD104 Antibody, clone 346-11A (RPE)

LM20011
貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)

Anti-Mouse CD104 Antibody, clone 346-11A (RPE)

品牌

Leading Biology

貨號(hào)

LM20011

產(chǎn)品分類(lèi)

單克隆抗體

研究領(lǐng)域

產(chǎn)品概述

Store at +4°C or at -20°C.

濃度

Rat anti-Mouse CD104 antibody, clone 346-11A recognizes mouse integrin beta 4 (CD104), a 200 kDa glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localised to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurones, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane.Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.

純度

Rat

復(fù)溶

1. Kennel, S.J. <i>et al.</i> (1992) The beta 4 subunit of the integrin family is displayed on a restricted subset of endothelium in mice.</br>J Cell Sci. 101 ( Pt 1): 145-50. 2. Kennel, S.J. <i>et al.</i> (1989) Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily.</br>J Biol Chem. 264 (26): 15515-21. 3. Moik, D.V. <i>et al.</i> (2011) Loss of migfilin expression has no overt consequences on murine development and homeostasis.</br>J Cell Sci. 124: 414-21. 4. L&auml;mmermann, T. <i>et al.</i> (2008) Rapid leukocyte migration by integrin-independent flowing and squeezing.</br>Nature. 453: 51-5. 5. Sonnenberg, A. <i>et al</i>. (1990) The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties.</br>J Cell Sci. 96:207-17. 6. Kennel, S.J. <i>et al</i>. (1986) Tumor antigen on benign adenomas and on murine lung carcinomas quantitated by a two-site monoclonal antibody assay.</br>Cancer Res. 46:707-12.

儲(chǔ)存條件

Mouse

儲(chǔ)存溶液

Integrin beta-4, CD104, Itgb4

數(shù)量

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