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HMGB 1是細胞核的一個組成部分，在基因組的組織和表達中具有多種功能。HMG生物技術(shù)SRL為活躍在這一領(lǐng)域的其他研究人員和公司提供試劑、服務和想法。它還有助于比安奇實驗室開發(fā)分析和試劑。
HMGB1 is a component of the cell nucleus, with multiple functions in the organization and expression of the genome. When a cell dies because of an insult (a virus, a mechanical or chemical trauma, poisoning) HMGB1 is released and is picked up by receptors in nearby cells. In addition, cells under severe stress secrete HMGB1 even before dying. Surviving cells mount a firstline response -inflammation- and try to replace the dead cells and reconstruct the damaged tissue. HMGB1 promotes recovery and regeneration, for example of the heart after infarction. However, too much HMGB1 is associated to sepsis (excessive inflammation leading to acute distress and eventually death), arthritis, atherosclerosis, and cancer metastasis.
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品牌 |
貨號 |
名稱 |
規(guī)格 |
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HMGBiotech |
HM-903 |
anti HMGB1 monoclonal antibody DPH1.1 |
1mg |
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HMGBiotech |
HM-902 |
anti HMGB1 monoclonal antibody DPH1.1 |
250ug |
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HMGBiotech |
HM-901 |
anti HMGB1 monoclonal antibody DPH1.1 |
50ug |
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